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高遷移率族蛋白1(HMGB1)多克隆抗體

參考價(jià)1361.00
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  • 公司名稱杭州昊鑫生物科技股份有限公司
  • 品       牌云克隆
  • 型       號(hào)PAA399Mu01
  • 所  在  地杭州市
  • 廠商性質(zhì)代理商
  • 更新時(shí)間2024/7/11 15:07:23
  • 訪問次數(shù)173
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杭州昊鑫生物科技股份有限公司成立于2009年初,是一家面向生命科學(xué)領(lǐng)域,從事科研機(jī)構(gòu)、高校、院所及生產(chǎn)企業(yè)所需科研試劑、耗材,儀器銷售和服務(wù)面向全國(guó)。

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胎牛血清、MCE抑制劑激動(dòng)劑、RNA提取試劑盒、ELISA試劑盒、重組蛋白
產(chǎn)地 進(jìn)口 規(guī)格 100ul
級(jí)別 化工級(jí) 證書 ISO系列證書
該抗體是針對(duì)HMGB1的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別HMGB1。
高遷移率族蛋白1(HMGB1)多克隆抗體 產(chǎn)品信息

高遷移率族蛋白1(HMGB1)多克隆抗體

Polyclonal Antibody to High Mobility Group Protein 1 (HMGB1)

HMG1; HMG3; SBP1; Sulfoglucuronyl Carbohydrate Binding Protein; Amphoterin; High Mobility Group Box 1 Protein

  • 編號(hào)PAA399Mu01

  • 物種Mus musculus (Mouse,小鼠) 相同的名稱,不同的物種。

  • 來源多抗制備

  • 宿主

  • 效價(jià)-

  • Ig類型IgG

  • 純化方式抗原特異性親和純化

  • 標(biāo)記物無標(biāo)記物

  • 免疫原RPA399Mu01-高遷移率族蛋白1(HMGB1)重組蛋白

  • 緩沖液成份0.01M 磷酸鹽緩沖液(pH7.4,containing 0.05% Proclin-300,50% glycerol)

  • 性狀液體

  • 濃度500µg/mL

  • 且適物種Homo sapiens (Human,人)

  • 應(yīng)用WB,IHC,ICC/IF
    如果抗體需用于流式細(xì)胞術(shù),請(qǐng)參見流式抗體。

  • 下載英文說明書   中文說明書

  • 規(guī)格20µl100µl 200µl 1ml 10ml

  • 價(jià)格¥ 1361


特異性

該抗體是針對(duì)HMGB1的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別HMGB1。

用法

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

儲(chǔ)存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定,具體方法如下:在37°C孵育48小時(shí),沒有明顯的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲(chǔ),損失率低于5%。

參考文獻(xiàn)

雜志參考文獻(xiàn)
Scandinavian Journal of Trauma, Resuscitation and Emergency MedicineHigh mobility group box protein-1 (HMGB-1) as a new diagnostic marker in patients with acute appendicitis [PubMed: PMC3094252]
RespirationProtective Effect of Nicotine on Lipopolysaccharide-Induced Acute Lung Injury in Mice [Karger: 000319151]
SurgeryClinical relevance of single nucleotide polymorphisms of the high mobility group box 1 protein gene in patients with major trauma in Southwest China [Pubmed: 22047946]
Viral ImmunologyIs HMGB1 a New Indirect Marker for Revealing Fibrosis in Chronic Hepatitis and a New Therapeutic Target in Treatment? [Wiley: source]
Chinese Medical JournalSeverity of sepsis is correlated with the elevation of serum high-mobility group box 1 in rats [CMJ: 2009218808935901080]
Microbiology and ImmunologyDiagnostic value of serum concentrations of high-mobility group-box protein 1 and soluble hemoglobin scavenger receptor in brucellosis [PubMed: 23278480]
ACTA biochimica polonicaHigh mobility group B1 levels in sepsis and disseminated intravascular coagulation [Actabp: Source]
Anesthesia and AnalgesiaThe Inhibitory Effect of Lidocaine on the Release of High Mobility Group Box 1 in Lipopolysaccharide-Stimulated Macrophages [PubMed: 21288974]
Rheumatology InternationalElevated serum levels of high mobility group box protein 1 (HMGB1) in patients with ankylosing spondylitis and its association with disease activity and quality of life [PubMed: 23143556]
Inflammation ResearchMammalian target of rapamycin complex 2 regulates inflammatory response to stress [PubMed: 22899279]
Acta Biochimica et Biophysica SinicaIGF-1 alleviates ox-LDL-induced inflammation via reducing HMGB1 release in HAECs [PubMed: 22782142]
LabVestThe suppression of TRIM21 and the accumulation of IFN-α play crucial roles in the pathogenesis of osteonecrosis of the femoral head. [PubMed: 22825687]
Biomark InsightsDecreased Epidermal Growth Factor (EGF) Associated with HMGB1 and Increased Hyperactivity in Children with Autism [PubMed: PMC3623607]
Evidence-based Complementary and Alternative MedicineATF3 Protects against LPS-Induced Inflammation in Mice via Inhibiting HMGB1 Expression [PubMed: PMC3770047]
Exp Ther MedCorrelation between serum high-mobility group box-1 levels and high-sensitivity C-reactive protein and troponin I in patients with coronary artery disease [Pubmed: 23935732]
International of Rheumatic disesasesSerum levels of high mobility group box 1 protein and its association with quality of life and psychological and functional status in patients with fibromyalgia [Pubmed: 23901875]
SurgeryA novel serum marker for biliary tract cancer: Diagnostic and prognostic values of quantitative evaluation of serum mucin 5AC (MUC5AC) [Pubmed: 24468034]
Acta Pharmacol Sin.Simvastatin suppresses vascular inflammation and atherosclerosis in ApoE-/- mice by downregulating the HMGB1-RAGE axis [Pubmed: 23564080]
BMC pulmonary medicineSoluble receptor for advanced glycation end-products and progression of airway disease [Pubmed: 24758342]
Biochemical PharmacologyAscorbic acid reduces HMGB1 secretion in lipopolysaccharide-activated RAW 264.7 cells and improves survival rate in septic mice by activation of Nrf2/HO-1 signals [Pubmed:25896849]
BioMed Research InternationalEffects of Single or Combined Treatments with Radiation and Chemotherapy on Survival and Danger Signals Expression in Glioblastoma Cell Lines [Hindawi:Source]
J Cardiothorac Surg.High plasma levels of high mobility group box 1 is associated with the risk of sepsis in severe blunt chest trauma patients: a prospective cohort study [Pubmed:Pmc4132233]
J Leukoc Biol.HMGB1 is an early and critical mediator in an animal model of uveitis induced by IRBP-specific T cells [Pubmed:24374967]
PLOS ONEThe Alarmin Concept Applied to Human Renal Transplantation: Evidence for a Differential Implication of HMGB1 and IL-33 [Pubmed:24586382]
Journal of Surgical ResearchPlasma levels of high mobility group box 1 increase in patients with posttraumatic stress disorder after severe blunt chest trauma: a prospective cohort study [Pubmed:25016440]



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